Ubiquitination-mediated Golgi-to-endosome sorting determines the toxin-antidote duality of fission yeast wtf meiotic drivers
Abstract Killer meiotic drivers (KMDs) skew allele transmission in their favor by killing meiotic progeny not inheriting the driver allele.Despite their widespread presence in eukaryotes, the molecular mechanisms behind their selfish behavior are poorly understood.In several fission yeast species, single-gene KMDs belonging to the 15-eg2373cl wtf g